Sunday 25 January 2015

Week 5 progress pics.


Where have we come in 5 weeks of using firstly Tea Tree Oil products and Ivermectin in the form of Ivomec?

Here are the first images taken November 29, 2014 followed by the most recent images taken today January 26, 2015.




















Without a doubt, there has been an improvement.

One week until I see my dermatologist.

I've focused on applying the Ivomec in the early evening (before the mites stir from their "homes") and again before I go to bed.  

The break outs are less common now.  There hasn't been a deep hot bump for a couple of weeks and the white-headed pimples are no longer a daily occurrence.  A dab of TTO comes to the rescue and quickly heals the spot.

While the skin on my cheeks still appears to be red, I'm wondering if it's a combination of vein damage and that it's just going to take a long time for my skin to heal now that I seem to have the mites under control.  I wouldn't want to address the issue of broken veins until I'm 100% confident that I can control the rosacea.

One week until I present myself to the dermatologist.




Friday 16 January 2015

Week 3 and the demodex fight back!

My skin, which was looking less inflamed into week 2, is now a battlefield of raised red bumps and surface whiteheads.  I am being woken around 2am by a sense of the mites moving over my face and brows and have been reapplying the Ivomec.  My pores seem to have enlarged again with the increase in activity over the past three days.

I had read in the Galderma trail results that there is a surge of activity at the week three mark and I'm certainly noticing it.  The fact that I am experiencing this using the Ivomec gives me hope that it is working in the same way as the SooLantra and am looking forward to a turnaround in week 4 and continued improvements onward from that point.

I am continuing the daily cleansing of my face with the TTO foaming facewash and the nightly application of Ivomec when the mites are moving from the pores in search of a breeding partner.

Two weeks to go until I see my dermatologist.



Sunday 4 January 2015

Seeing results with Ivermectin.

After one week of using Ivomec twice daily after cleansing, I'm seeing an improvement.  I noted that Galderma's patients saw improvement by the 2 week mark with a decline in skin condition (increased pimples and pustules) around the 3rd week and then further improvement from the 4th week.  



My observations using Ivomec are that around the 3rd day I experienced a substantial breakout of surface-based whiteheads across both cheeks and lesser so on my neck, decolletage and across my upper back.  It should be noted that I was not applying the Ivomec onto my upper back.  Within 2 days, the whiteheads are clearing with only the occasional one appearing.  In the last 7 days there have not been any of the painful, deeper cystic-type swellings.

Each time I have applied the Ivomec, I have noticed a slight warming sensation of the skin.  The feeling dissipates within seconds.  There is no accompanying flushing of the skin, it's is only a sensation.  I don't know if the sensation is due to the ivermectin itself but I suspect it is more likely to be from one of the carrier ingredients (glycerol formal or propylene glycol) and I'll bet it is specifically the propylene glycol which is used in personal lubricant products because of the warming sensation it provides. 

Regarding the safety of using Ivomec to treat my rosacea, I have found the following information: 
Ivermectin works by disrupting nerve impulses in parasites. It binds to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells which leads to an increase in the permeability of the cell membrane, thereby paralyzing and killing the invaders.

The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated chloride channels, the macro-cyclic lactones have a low affinity for other mammalian ligandgated chloride channels and they do not readily cross the blood-brain barrier.

Source: http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=27632

It's exactly one month until my appointment with my dermatologist.